About Dr. Payne

Meet Dr. Karroll Payne

Dr. Karroll Payne is an experienced OB/GYN serving women in Lafayette and the surrounding Acadiana area. She provides personalized gynecologic care for women through every stage of life, from preventive visits and reproductive health to menopause care and surgical treatment when needed.
Patients choose Dr. Payne because they want a physician who listens carefully, explains their options clearly, and takes the time to understand what is really going on. Her approach is thoughtful, direct, and compassionate.
Dr. Payne’s background combines strong clinical experience with a practical, problem-solving approach to women’s health. She helps patients understand their symptoms, review their options, and make informed decisions about their care.
Her areas of care include annual wellness visits, gynecology, menopause support, abnormal bleeding, pelvic pain, hormone-related concerns, and surgical gynecology.

Dr. Payne’s Care Philosophy

Women deserve healthcare that feels personal, respectful, and clear. Dr. Payne believes patients should understand their bodies, their diagnosis, and their treatment options before making decisions.
Her goal is to create an appointment experience where patients feel heard, not rushed, and where concerns are taken seriously.

What You Can Expect

Welcome to Our Practice

We are pleased you selected Dr. Karroll Payne and her dedicated staff to meet your healthcare needs, and it is our honor to serve you with competent and compassionate care. When you visit our office, you will quickly discover you are our HIGHEST priority!

We work hard to provide you with the best healthcare services with a personal touch. You are not just another chart- you are one of our beloved patients, and we treat you with the respect and attention you deserve.

As a Board- Certified Obstetrician and Gynecologist., Dr Karroll Payne offers comprehensive health care for women in the New Orleans & Northshore area. Dr. Payne was born and raised in Louisiana and, after nearly 20 years of successful practice in Atlanta, decided to move home to Louisiana to raise her family, which includes a husband and three children. Dr. Payne understands the unique needs of her patients and strives to provide culturally competent care. She is also well-versed in Vaginal Surgery techniques that allow the fastest recovery with the least pain for her patients.

Innovative Methods

Combining years of clinical experience with a deep compassion for women, Dr. Payne and her friendly staff create a welcoming environment where patients are at ease even during difficult medical situations. We use cutting-edge technology to ensure our patients receive the best diagnostic and preventive care. Her encrypted EMR system offers a user-friendly patient interface with copies of all lab results and imaging studies immediately available for patients to view and the ability to view and send emails to the doctor privately and securely.

When you visit our office, we encourage you to be an active, informed participant in your healthcare. Feel free to ask questions and voice your concerns… we want to help. We look forward to partnering with you as your women’s healthcare provider from puberty to the end of life.

Visit Us in Lafayette

K. Payne M.D. is located at 913 S College Rd, Suite 216-A, Lafayette, LA 70503. Look for the white brick building with 913 on the front. Parking is available on-site.
Business Hours
Please do not use online scheduling for emergencies. If you are experiencing a medical emergency, Call 911 .